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Daren Labs is a Scientific consultancy company and labs facilities for startups performing custom R&D and provide expert knowledge to commercial, government and private customers working alongside startup companies and investors. MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Synthesis and Formulation YEARS OF HANDS-ON EXPERIENCE MAKE DAREN LABS A LEADER IN SYNTHESIS AND FORMULATION DEVELOPMENT. Over the years we have gained extensive experience in developing custom synthesis and formulations for a wide range of materials in diverse applications. Whether you have a reference material or spec you would like to duplicate or a set of properties you would like to tailor/reverse engineer - our chemists can do it. Among the materials and formulations we’ve developed in the past are: pharmaceuticals, membranes, coatings, flame retardants, optical and bio polymers, adhesives, dental implants, chemical sensors and bio-active materials. We can also help you scale up the processes as well as provide small-scale (gram to kilo) production of the developed materials. Our team can work hand-in-hand with you or lead a full scale project solution – according to your client. Why invest in building R&D capabilities when you can have our team of experts develop new strategic materials or formulations for you, faster, cheaper and discreetly with no IP claims? Contact us to learn more

Daren Labs is a Scientific consultancy company and labs facilities for startups performing custom R&D and provide expert knowledge to commercial, government and private customers working alongside startup companies and investors. MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Analytical Lab Services Download PDF Differential Scanning Calorimetry (DSC 6000 – Perkin Elmer) The differential scanning calorimeter (DSC) is a fundamental tool in thermal analysis. The information these instruments generate is used to understand amorphous and crystalline behavior, polymorph and eutectic transitions, curing and degree of cure, and many other material properties used to design, manufacture, and test products. It can be used in many industries – from pharmaceuticals and polymers, to nanomaterials and agrifood products. DSC analysis is used to measure melting temperature, heat of fusion, latent heat of melting, reaction energy and temperature, glass transition temperature, crystalline phase transition temperature and energy, precipitation energy and temperature, denaturation temperatures, oxidation induction times, and specific heat or heat capacity. By measuring the amount of energy absorbed or released by non-corrosive sample when it is heated or cooled, DSC analysis provide quantitative and qualitative data on endothermic (heat absorption) and exothermic (heat evolution) processes. Thermogravimetric analysis or thermal gravimetric analysis (TGA 8000– Perkin Elmer) Thermogravimetry Analysis (TGA) is the technology for measuring the relationship between mass and temperature (or time), under heating or cooling process, or under constant temperature, while the temperature is under control. TGA measures weight/mass change (loss or gain) and the rate of weight change as a function of temperature, time and atmosphere. Measurements are used primarily to determine the composition of materials and to predict their thermal stability. The technique can characterize materials that exhibit weight loss or gain due to sorption/desorption of volatiles, decomposition, oxidation and reduction. Mechanisms of Weight Change in TGA 1 Weight Loss: Decomposition: The breaking apart of chemical bonds. Evaporation: The loss of volatiles with elevated temperature. Reduction: Interaction of sample to a reducing atmosphere (hydrogen, ammonia, etc.). Desorption. 2 Weight Gain: Oxidation: Interaction of the sample with an oxidizing atmosphere. Absorption. All of these are kinetic processes (i.e. there is a rate at which they occur). Download PDF Example: Characterization of Polymers Using TGA W.J. Sichina, Marketing Manager – Washinton dep.edu • Compositional analysis of multi-component materials or blends • Thermal stabilities • Oxidative stabilities • Estimation of product lifetimes • Decomposition kinetics • Effects of reactive atmospheres on materials • Filler content of materials • Moisture and volatiles content Other currents applications: Ceramics, Metal Materials, Flame Retardant, Carbon capture, Chemical loop, Vegetable Oil Oxidative Stability, Polymer Applications, and others Spectrum obtained can be analysis compare We can analyze following type of samples Soft polymers, Rubbers, thin film* Soft powders, Pastes, Gels, Aqueous solutions Surface coatings Organic products Proteins and other biochemical Comparison of plant extract. Impurity included a pure reference sample. Fourier transform infrared spectroscopy (FTIR ) FTIR is characterization technique used in qualitative material analysis within the biological, biomedical and chemical industry; this technique takes advantage of the vibrational transitions of a molecule and is widely used in organic synthesis, polymer science, petrochemical engineering, pharmaceutical industry and food analysis. FTIR is a method of measuring infrared absorption and emission spectra. In organic or inorganic compounds, IR Spectroscopy is used for checking presence of functional groups. The fundamental measurement obtained in infrared spectroscopy is an infrared spectrum, which is a plot of measured infrared intensity versus wavelength (or frequency) of light. Units of cm-1 is commonly used for wavenumber. *By transmission, analyzing of Thin Films* should be in the freestanding condition and thickness should be ≤ 50μm. Thicker film can be analyzed By ATR Attenuated total reflection (ATR) spectroscopy ATR is one accessory of FTIR spectrophotometer to measure surface properties of solid or thin film samples rather than their bulk properties. Generally, ATR has a penetration depth of around 1 or 2 micrometers depending on your sample conditions. The infrared radiation interacts with the sample through series of standing waves called evanescent waves, which penetrate the sample at each reflection point. An evanescent wave is produced each time the infrared beam is reflected from the inside surface of the crystal. Some of the energy of evanescent wave is absorbed by the sample and reflected radiation is returned to the detector. Link to website Download PDF Fourier transform infrared spectroscopy (FTIR ) The technique is based on absorption of light. In molecular absorbance spectroscopy, a beam of ultraviolet or visible light is directed through a sample. Some of the light may be transmitted through the sample. Instrument measures transmitted light. Light that was not transmitted through the sample was absorbed. Absorbance (A) is defined as -log(P/Po). Beer Lambert Law States that absorbance of electromagnetic radiation by a given species is directly proportional to the concentration of the analyte. It is expressed as: A= εbC • where A is the absorbance, ε is the molar absorptivity, b is the path length and C is the concentration of analyte. Because ε and b are fixed under experimental conditions, the result is a linear relationship between absorbance and concentration. Viscometer DV-II Brookfield The Brookfield DV-II+Pro Viscometer measures fluid viscosity at given shear rates. Viscosity is a measure of a fluid’s resistance to flow. The Viscometer rotates a sensing element in a fluid and measures the torque necessary to overcome the viscous resistance to the induced movement. This is accomplished by driving the immersed element, which is called a spindle, through a beryllium copper spring. The degree to which the spring is wound, indicated by the red pointer, is proportional to the viscosity of the fluid. All units of measurement are calculated in units of centipoise (cP); SI: 1 cP = 1 mPa•s Download PDF Loss on Drying (LOD) A method commonly used for moisture content determination is the loss-on-drying method. Occasionally it may refer to the loss of any volatile matter from the sample. Download PDF Freeze dryer or Lyophilizer Lyophilizer and freeze dryer are synonymous names for the same equipment. A lyophilizer executes a water removal process typically used to preserve perishable materials, to extend shelf life or make the material more convenient for transport. Lyophilizers work by freezing the material, then reducing the pressure and adding heat to allow the frozen water in the material to sublimate. Controlled freeze-drying keeps the product temperature low enough during the process to avoid changes in the dried product appearance and characteristics. It is an excellent method for preserving a wide variety of heat-sensitive materials such as proteins, microbes, pharmaceuticals, tissues & plasma. High-performance liquid chromatography (HPLC) High performance liquid chromatography or commonly known as HPLC is an analytical technique used to separate, identify or quantify each component in a mixture. HPLC works following the basic principle of thin layer chromatography or column chromatography, where it has a stationary phase and a mobile phase. The mobile phase flows through the stationary phase and carries the components of the mixture with it. The mixture is separated and then identified and quantified by spectroscopy. A computer analyzes the data show the output in display.

Subcontracting your R&D projects isn’t an easy decision to make. However, with the right partner contract R&D can be a cost-effective way to get results, faster. MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contract R&D Subcontracting your R&D projects isn’t an easy decision to make. However, with the right partner contract R&D can be a cost-effective way to get results, faster. Our team of experts leads dozens of materials-development project annually, working closely with our clients, making sure results meet the goal. Our long-year diverse experience, in-house lab infrastructure and analytics, allow us to develop custom solutions efficiently. In cases of specialty materials development, we are also able to manufacturer the developed product (kilo scale batches). Some contract R&D projects we can mention: Development of polymeric membrane for flexible batteries (technology commercialized). Developed cross-linking procedures for hyaluronic acid hydrogels Developed and scaled up a five-stage synthesis of a new steroid drug for Fatty Liver Disease (now in phase III trials) Reverse engineering and pilot production of a bio-degradable polymer for orthopedic implants. Development of UV sensitive photochromic coating for optical equipment. Daren labs produces this material for the OEM. Developed an acrylic surface coating that enhances the shelf-life of cut flowers (technology commercialized). Contact us to learn more

Alongside our role as technology leaders, we leverage our vast network and experience to guide startups and connect between technologies and capital. MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Technology Scouting Having served 100s of companies, innovators, startups and investors, we developed a unique perspective about the way materials technology should be developed. Whether 3D printing materials, medical devices, energy harvesting or food formulations, we have seen it all. Alongside our role as technology leaders, we leverage our vast network and experience to guide startups and connect between technologies and capital. If you are an investor, VC, or corporation seeking materials technologies ‘made in Israel’, you are welcome to contact us and ask about our tech scouting services. Hyundai Motor and Daren Labs join forces in the search for Israeli companies developing advanced materials for next generation car production. Contact us to learn more

We offer high-quality lyophilization (freeze-drying) services using advanced, state-of-the-art lyophilizers. Our services are available to both in-house lab tenants and external companies and are suitable for small R&D samples as well as larger-scale preparations (up to 5 litters). MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Freeze-Drying We offer high-quality lyophilization (freeze-drying) services using advanced, state-of-the-art lyophilizers. Our services are available to both in-house lab tenants and external companies and are suitable for small R&D samples as well as larger-scale preparations (up to 5 litters) . Our systems enable efficient and gentle drying , while preserving the stability and integrity of your materials. Applications in Chemistry • Drying of moisture-sensitive compounds • Production of stable powders from solutions or suspensions • Drying of polymers, resins, and intermediates • Water removal without thermal degradation • Long-term stabilization of chemical formulations Applications in Life Sciences & Biotechnology • Lyophilization of proteins, peptides, enzymes, and antibodies • Drying of cell cultures and microbial samples • Stabilization of vaccines and diagnostic reagents • Drying of buffers, media, and culture supplements • Preparation of powders for research, storage, or further development Why Choose Us? • Advanced and precise equipment • Suitable for both research and industrial projects • Experience with sensitive materials • Flexible volumes (from small samples up to 5 liters) • Convenient service for lab tenants and startup companies Frequently Asked Questions (FAQ) How long does the lyophilization process take? It depends on the sample. Can sensitive biological samples be freeze-dried? Yes, the process is especially suitable for proteins, enzymes, and cells. What is the maximum volume per run? Up to 5 liters per cycle. Interested in professional and reliable freeze-drying services? Contact us for more information and a customized quote. Contact us to learn more

Production of physical products always involves materials processing. MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Problem Solving Production of physical products always involves materials processing. Whether in electronic circuits, fabrics, medical tubing or car tires, sometimes things go wrong. In many cases, end-users and brand owners are not familiar with the various materials and processes involved in the making of their products and need our assistance. Identifying the root cause of a failed batch, loss of performance or change of color requires the application of multidisciplinary tools. Once identified, we recommend corrective actions and support our clients back to spec. Some problems we helped solve: Plastic components showed poor bonding during production of medical device. Food package generating a strong smell after sealing process Unidentified “black spots” identified after production of a cosmetic lotion Degradation of the performance of a cooling fluid passing in new a multi materials system Variation of protection coating color used in electronics component manufacturing Contact us to learn more

We use a range of advanced analytical tools during our day-to-day work. Whether for contract R&D product development, problem solving projects or defined materials analysis requests, we always provide full interpretation of the results. MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Analytical Capabilities We use a range of advanced analytical tools during our day-to-day work. Whether for contract R&D product development , problem solving projects or defined materials analysis requests, we always provide full interpretation of the results. We operate both chemical and physical analytical tools including: Thermal spectroscopy: TGA, DSC Light spectroscopy: UV-Vis, FTIR Analytical Chromatography: High-performance liquid chromatography (HPLC) Rheometer (rotational shear): elastic and viscoelastic flow characterization, static and dynamic states, Thixotropic behaviour analysis Viscosity (Brookfield): spindle test Loss on Dry (LoD) Lyophilization (freeze drying) Mechanical: tensile test (Instron) Electric: 4-point probe sheet resistance Texture Analyzer Sonication We also have direct access to additional analytical tools such scanning electron microscope (SEM), ICP, NMR and others. Contact us to learn more

Daren Labs is a Scientific consultancy company and labs facilities for startups performing custom R&D and provide expert knowledge to commercial, government and private customers working alongside startup companies and investors. MATERIALS EXPERTS Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Freeze Drying Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Production & Scale-up Together with our contract R&D services, we also offer our clients scale-up and production services. Our capabilities and experience allow us to take production projects of batches in the kilogram range. Such services are suitable for either: Start up companies scaling up volumes during go-to-market stage (beta testing volumes) Veteran companies in need for custom chemicals at limited quantities (specialty chemicals) Examples for some of the chemicals we produce for our clients include: Photo-chromic coating, optical adhesives, PVC solutions for graphic arts, buffers for medical applications, fluorescent dies for plastic industry, polymers for composite materials, CBD formulations, nano-clays for water treatments and many others. Once produced, the products undergo chemical analysis according to customer requirements. Contact us to learn more

Daren Startup Labs division is the leading co-working labs for startups in Israel. A place where you can have a lab, then test, develop and grow your ground-breaking ideas START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Labs Design Fully equipped labs, expert support, and everything you need to grow smarter and faster Daren Startup Labs division is the leading co-working labs for startups in Israel. A place where you can have a lab, then test, develop and grow your ground-breaking ideas. Similar to other shared workspace models , we provide a turn-key solution for lab rentals and scientific services . This way startups can remain devoted exclusively to their research & development, avoiding unnecessary time and money invested in infrastructure and logistics. PROFESSIONAL EQUIPMENT Access to advanced analytical equipment and in-house consultancy services FLEXIBILITY Flexible lease, commit to a convenient time period TIME IS MONEY You can start up quickly with a fully equipped lab or according to your budget NO IP CLAIMS We make no claims over the IP you develop FOCUS All the logistics, HZ materials, FD permits and more are our responsibility, leaving you 100% focused on R&D CARE & SUPPORT IS OUR MOTO HELPING YOU GROW IN ANY WAY WE CAN Advanced Workspaces Remarkable Experiences Contact us to learn more The way we see it, your success is our goal! KEY REASONS TO USE DAREN LABS IN YOUR NEXT PROJECT Since 2017 we helped the launch of over 120 startups + 120 Startups Our member-launched startups have created over 800 jobs + 800 Jobs Our members collectively raised over 1B in financing $ 1B Raised

Daren Labs provide expert opinions in chemistry and materials science, based on in-depth testing, rigorous scientific analysis, and the ability to present clear, well-supported conclusions in court. Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Expert Opinion Services for Court in Chemistry and Materials When a legal case depends on a professional question, a single precise expert opinion can make the difference between losing and winning. We provide expert opinions in chemistry and materials science, based on in-depth testing, rigorous scientific analysis, and the ability to present clear, well-supported conclusions in court. Not all expert opinions are created equal In many cases, general or superficial opinions fail to uncover the root cause and sometimes even reinforce incorrect conclusions. Our advantage lies in our ability to: ✅ Go deep into the material not rely on assumptions ✅ Identify failures that other experts miss ✅ Base conclusions on actual testing, not just theoretical analysis When do we get involved? ➡️ Product or component failure (fracture, corrosion, degradation) ➡️ Claims of defective manufacturing or material flaws ➡️ Disputes between contractors, suppliers, and developers ➡️ Compliance testing against standards and specifications ➡️ Failure analysis Who is this service for? Law firms (litigation, torts, commercial law) Contractors facing claims related to defects Suppliers and importers who need to defend their products How does the process work? 1. Rapid case assessment Review of documents, existing expert opinions, and identification of key dispute points 2. Targeted laboratory testing Identification of real failures at the material and component level 3. Clear, evidence-based conclusions Not “maybe” but definitive professional determinations 4. Court-admissible expert opinion Clear, structured writing that speaks to judges, attorneys, and experts alike 5. Expert testimony support (if required) Real Case Example In a case where the defendant was accused of causing significant damage due to human error, all other expert opinions supported this claim. A thorough examination by one of our experts of the material components revealed a completely different picture. The failure was caused by defective manufacturing of the component — not by the defendant’s actions. This conclusion changed the course of the case. Dear Dr. Daren, I wanted to update you that your expert opinion made all the difference in the case and prevented a ruling against the defendant (our client), which would have resulted in compensation of 600,000 NIS — even though he was not at fault. Your opinion clearly demonstrated to the judge, the mediator, and all involved parties that the significant damage was caused by a manufacturing defect in the connector not by human error, as claimed by the other experts. Daren Labs was the only party that conducted a thorough examination of the connector components, and it was only through this in-depth analysis that the defects and failures in the product were identified. Beyond that, it was a pleasure working with you. You demonstrated high professionalism, patience, and availability throughout the process. I have no doubt that for any future need, Daren Labs will be my first choice. Thank you very much! Sincerely, Adv. A. Klein ❌ An inaccurate expert opinion can: • Lead to losing the case • Create significant financial exposure • Establish a flawed conclusion that is difficult to overturn ✅ A well-founded expert opinion can: • Change the direction of the case • Significantly strengthen your position • Lead to a faster and more favorable settlemen Let’s evaluate your case If you are dealing with a case involving a materials-related dispute, contact us for an initial assessment. Contact us

Daren Materials Experts division is a one-stop-shop for materials development and problem-solving, supporting the Israeli industry and startup eco-system providing results where chemistry and materials pose a significant challenge Home experts Expert Opinion For Court Services Contract R&D Synthesis & Formulation Scale up & Production Problem Solving Analytical Capabilities Tech Scouting DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Daren Labs Materials Experts Daren Labs Materials Experts Daren Labs Materials Experts Daren Labs is a one-stop shop for materials development and problem solving, supporting Israeli industry since 1990. The company was founded by Dr. Steve Daren, a graduate of the Weizmann Institute of Science and a globally recognized expert in chemistry and polymers. Advanced Materials Development Laboratory Our expert team includes chemists, materials engineers, and researchers with broad expertise. We support every project from the initial concept through development and all the way to the finished product. We work closely with our clients to deliver precise, reliable, and fully customized solutions tailored to their specific needs. Our services include: Development of new materials tailored to customer requirements Improvement and optimization of existing materials Advanced testing, analysis, and material characterization Scientific and technological consulting Support and guidance throughout production and implementation processes Experienced and highly qualified expert team Commitment to quality, precision, and meeting deadlines Advanced laboratory equipment and innovative technologies Personalized approach and close project support Why to chose us? We are committed to delivering advanced solutions that promote innovation, efficiency, and competitive advantage for our clients. Contact us to learn more We invite you to join our partners in shaping the future of materials science if you are looking for: A materials development laboratory Custom synthesis according to protocol Custom materials development Materials science experts Formulation development Looking for renting fully equipped co-working labs? Daren Startup Labs offer flexible shared laboratory space for the real needs of researchers and startups. You will find supportive scientific community, fully furnished and equipped labs, analytical instruments, and professional consulting. Daren Startup Labs

Daren Labs is a Scientific consultancy company and labs facilities for startups performing custom R&D and provide expert knowledge to commercial, government and private customers working alongside startup companies and investors. MATERIAL EXPERTS GET IN TOUCH We will be happy to provide any additional information. Just leave your details below, and we will contact you. Full name* Phone* Email* Company name* Our Services* Contract R&D Write a message* I agree to receive updates from Daren Labs * Submit Full Name Company Email Phone Choose field Details I agree to recive upates fom DarenLabs Send Tel. :08-9402942 Mail: info@darenlabs.com Fax :08-9409925 Address : 3 Pinhas Sapir St, Ness Ziona, 7403626 Israel