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MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us MEET THE TEAM Dr. Steve Daren President & Founder Dr. Shai Garty R&D Project Leader Dr. Anna Munder R&D Project Leader Sagi Daren Chief Business Officer Vlada Nikolayevsky (MSc.) R&D Chemist & Lab Manager Pavel Basin (MSc.) R&D Chemist Ofra Cohen Bookkeeper

Materials Experts Materials Experts Home Services The Team Accessibility Statement Verticals Testimonials Contact Us More Download PDF Differential Scanning Calorimetry (DSC 6000 – Perkin Elmer) The differential scanning calorimeter (DSC) is a fundamental tool in thermal analysis. The information these instruments generate is used to understand amorphous and crystalline behavior, polymorph and eutectic transitions, curing and degree of cure, and many other material properties used to design, manufacture, and test products. It can be used in many industries – from pharmaceuticals and polymers, to nanomaterials and agrifood products. DSC analysis is used to measure melting temperature, heat of fusion, latent heat of melting, reaction energy and temperature, glass transition temperature, crystalline phase transition temperature and energy, precipitation energy and temperature, denaturation temperatures, oxidation induction times, and specific heat or heat capacity. By measuring the amount of energy absorbed or released by non-corrosive sample when it is heated or cooled, DSC analysis provide quantitative and qualitative data on endothermic (heat absorption) and exothermic (heat evolution) processes. Thermogravimetric analysis or thermal gravimetric analysis (TGA 8000– Perkin Elmer) Thermogravimetry Analysis (TGA) is the technology for measuring the relationship between mass and temperature (or time), under heating or cooling process, or under constant temperature, while the temperature is under control. TGA measures weight/mass change (loss or gain) and the rate of weight change as a function of temperature, time and atmosphere. Measurements are used primarily to determine the composition of materials and to predict their thermal stability. The technique can characterize materials that exhibit weight loss or gain due to sorption/desorption of volatiles, decomposition, oxidation and reduction. Mechanisms of Weight Change in TGA 1 Weight Loss: Decomposition: The breaking apart of chemical bonds. Evaporation: The loss of volatiles with elevated temperature. Reduction: Interaction of sample to a reducing atmosphere (hydrogen, ammonia, etc.). Desorption. 2 Weight Gain: Oxidation: Interaction of the sample with an oxidizing atmosphere. Absorption. All of these are kinetic processes (i.e. there is a rate at which they occur). Example: Characterization of Polymers Using TGA W.J. Sichina, Marketing Manager – Washinton dep.edu • Compositional analysis of multi-component materials or blends • Thermal stabilities • Oxidative stabilities • Estimation of product lifetimes • Decomposition kinetics • Effects of reactive atmospheres on materials • Filler content of materials • Moisture and volatiles content Other currents applications: Ceramics, Metal Materials, Flame Retardant, Carbon capture, Chemical loop, Vegetable Oil Oxidative Stability, Polymer Applications, and others Download PDF Spectrum obtained can be analysis compare We can analyze following type of samples Soft polymers, Rubbers, thin film* Soft powders, Pastes, Gels, Aqueous solutions Surface coatings Organic products Proteins and other biochemical Comparison of plant extract. Impurity included a pure reference sample. Fourier transform infrared spectroscopy (FTIR ) FTIR is characterization technique used in qualitative material analysis within the biological, biomedical and chemical industry; this technique takes advantage of the vibrational transitions of a molecule and is widely used in organic synthesis, polymer science, petrochemical engineering, pharmaceutical industry and food analysis. FTIR is a method of measuring infrared absorption and emission spectra. In organic or inorganic compounds, IR Spectroscopy is used for checking presence of functional groups. The fundamental measurement obtained in infrared spectroscopy is an infrared spectrum, which is a plot of measured infrared intensity versus wavelength (or frequency) of light. Units of cm-1 is commonly used for wavenumber. *By transmission, analyzing of Thin Films* should be in the freestanding condition and thickness should be ≤ 50μm. Thicker film can be analyzed By ATR Attenuated total reflection (ATR) spectroscopy ATR is one accessory of FTIR spectrophotometer to measure surface properties of solid or thin film samples rather than their bulk properties. Generally, ATR has a penetration depth of around 1 or 2 micrometers depending on your sample conditions. The infrared radiation interacts with the sample through series of standing waves called evanescent waves, which penetrate the sample at each reflection point. An evanescent wave is produced each time the infrared beam is reflected from the inside surface of the crystal. Some of the energy of evanescent wave is absorbed by the sample and reflected radiation is returned to the detector. Link to website Download PDF Fourier transform infrared spectroscopy (FTIR ) The technique is based on absorption of light. In molecular absorbance spectroscopy, a beam of ultraviolet or visible light is directed through a sample. Some of the light may be transmitted through the sample. Instrument measures transmitted light. Light that was not transmitted through the sample was absorbed. Absorbance (A) is defined as -log(P/Po). Beer Lambert Law States that absorbance of electromagnetic radiation by a given species is directly proportional to the concentration of the analyte. It is expressed as: A= εbC • where A is the absorbance, ε is the molar absorptivity, b is the path length and C is the concentration of analyte. Because ε and b are fixed under experimental conditions, the result is a linear relationship between absorbance and concentration. Download PDF Viscometer DV-II Brookfield The Brookfield DV-II+Pro Viscometer measures fluid viscosity at given shear rates. Viscosity is a measure of a fluid’s resistance to flow. The Viscometer rotates a sensing element in a fluid and measures the torque necessary to overcome the viscous resistance to the induced movement. This is accomplished by driving the immersed element, which is called a spindle, through a beryllium copper spring. The degree to which the spring is wound, indicated by the red pointer, is proportional to the viscosity of the fluid. All units of measurement are calculated in units of centipoise (cP); SI: 1 cP = 1 mPa•s Loss on Drying (LOD) A method commonly used for moisture content determination is the loss-on-drying method. Occasionally it may refer to the loss of any volatile matter from the sample. Download PDF Freeze dryer or Lyophilizer Lyophilizer and freeze dryer are synonymous names for the same equipment. A lyophilizer executes a water removal process typically used to preserve perishable materials, to extend shelf life or make the material more convenient for transport. Lyophilizers work by freezing the material, then reducing the pressure and adding heat to allow the frozen water in the material to sublimate. Controlled freeze-drying keeps the product temperature low enough during the process to avoid changes in the dried product appearance and characteristics. It is an excellent method for preserving a wide variety of heat-sensitive materials such as proteins, microbes, pharmaceuticals, tissues & plasma. High-performance liquid chromatography (HPLC) High performance liquid chromatography or commonly known as HPLC is an analytical technique used to separate, identify or quantify each component in a mixture. HPLC works following the basic principle of thin layer chromatography or column chromatography, where it has a stationary phase and a mobile phase. The mobile phase flows through the stationary phase and carries the components of the mixture with it. The mixture is separated and then identified and quantified by spectroscopy. A computer analyzes the data show the output in display.

MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Production & Scale-up Together with our contract R&D services, we also offer our clients scale-up and production services. Our capabilities and experience allow us to take production projects of batches in the kilogram range. Such services are suitable for either: Start up companies scaling up volumes during go-to-market stage (beta testing volumes) Veteran companies in need for custom chemicals at limited quantities (specialty chemicals) Examples for some of the chemicals we produce for our clients include: Photo-chromic coating, optical adhesives, PVC solutions for graphic arts, buffers for medical applications, fluorescent dies for plastic industry, polymers for composite materials, CBD formulations, nano-clays for water treatments and many others. Once produced, the products undergo chemical analysis according to customer requirements. Contact us to learn more

Search Results 45 items found for "" Daren Labs | Scientific consultancy and labs facilities | Israel Daren Labs is a crossroads where industry, science, people and business opportunities meet DAREN STARTUP LABS Daren Startup Labs division is the leading co-working labs for startups in Israel. ​ A place where you can have a lab, then test, develop and grow your ground-breaking ideas DAREN MATERIALS EXPERTS Daren Materials Experts division is a one-stop-shop for materials development and problem-solving, supporting the Israeli industry and startup eco-system providing results where chemistry and materials pose a significant challenge Analytical Capabilities | Materials Experts | Daren Labs Analytical Capabilities We use a range of advanced analytical tools during our day-to-day work. ​ Whether for contract R&D product development , problem solving projects or defined materials analysis requests, we always provide full interpretation of the results. ​ We operate both chemical and physical analytical tools including: Thermal spectroscopy: TGA, DSC Light spectroscopy: UV-Vis, FTIR Chromatography: High-performance liquid chromatography (HPLC) Rheometry (rotational shear): elastic and viscoelastic flow characterization, static and dynamic states, Thixotropic behaviour analysis Viscosity (Brookfield): spindle test Loss on Dry (LoD), Lyophilization (freeze drying) Mechanical: tensile test (Instron) Electric: 4-point probe sheet resistance ​ We also have direct access to additional analytical tools such scanning electron microscope (SEM), ICP, NMR and others. Contact us to learn more MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Equipment | Start Up Here | Daren Labs START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact IN OUR LAB SITES YOU WILL FIND WORLD CLASS LAB EQUIPMENT PCR PCR Thermocycler Blue-Ray biotech ​ Temperature range +4 °C-99 °C ; Fast heating ramp rate up to 5.5 °C/sec ; Excellent temperature accuracy and uniformity (+/- 0.3 °C) ; 12-section gradient temperature range from 1 to 24.9 °C for PCR optimization ; The quick boot-up takes only 45 seconds. Biometra Temperature range -3°C-99 °C temperature accuracy and uniformity (+/- 0.1 °C) RT-PCR Bio Rad CFX96TM Analysis methods: PCR quantification, Gene expression, Melt curve analysis, Allelic discrimination, End point analysis ; Temperature range 0-100°C +/-0.2°C, Range of ext./em. 450-730nm ; 96 wells: from1μL-50 μL (recommended 10μL-25 μL). Mx3000p QPCR System Agilent Mx3000p QPCR System Agilent - Analysis methods: Quantitative PCR, Comparative Quantitation, SYBR Green, Allele Discrimination, Melting curve. 4 dyes per well Microscope Olympus Fluorescence Microscope inverted CKX53 Olympus x4, x10, x20 + Fluorescence GFP, RFP, DAPI Brightfield, Phase Contrast, and DIC only Motic Optical Microscope x4, x10, x40, x100 + Camera 5M Olympus Binocular Microscope up to x90 + Camera 15M Plate Reader Synergy HT Multi-Mode Microplate Reader - Capable of reading any plate format up to 384-well plates and provides temperature control up to 50° C and shaking as standard features. Typical applications include antibody-antigen binding, receptor-liquid binding, ELISA, nucleic acid quantitation Absorbance monochromator from 200 nm to 999 nm (UV -Vis). Fluorescence (ext./em. 485/530, 528/590, 485/590). Luminescence. ​ Thermo scientific Multiskan FC - Plate types – 96 or 348 well plate ; Wavelength – 405nm, 450nm, 620nm ; Shaker – Slow (5 Hz, amplitude 15 mm), Medium (11 Hz, amplitude 3 mm), and Fast (20 Hz, amplitude 1 mm) ; Temperature range - +4°C to 50°C. PHOmo Microplate reader - Detection method: Absorbance ; Measurement modes: Endpoint & Kinetic ; Plate type: 96, 48 flat, U and V bottom ; Filters 405nm, 450nm, 492nm, 620nm. Flow cytometry - FACS CytoFLEX Beckman Coulter Life Science Flow cytometr Laser specification- Violet (ex.405nm), Blue (ex.488), Red (ex.638). 30 000 events per second with all configured parameters. Nano Drop Micro-Spectrophotometer Fluorometer DeNovix DS-11 FX Rapidly quantify seven orders of magnitude of nucleic acids and protein samples selecting your choice of UV-Vis or Fluorescent modes. ​ Full spectrum UV-Vis analysis (190n m to 840 nm) Fluorescence capability: Green LED : 525 nm (Excitation), 565 to 650 nm (Emission) Red LED : 632 nm (Excitation), 665 to 740 nm (Emission) Blue LED : 470 nm (Excitation), 514 to 567 nm (Emission) UV : 375 nm (Excitation), 435 to 485 nm (Emission) NanoDrop 2000 Thermo Scientific Applications: Nucleic acid, Protein, Fluorescent dye corporation, BCA Assays, Bradford, Kinetic methods, Custom methods ; Full spectral output (190 - 840 nm) ; Preconfigured methods for A260, A280, labeled DNA or Proteins, and much more. Gel Imaging system Omega lum Semi-Quantitative Assay EtBr, SYBR Green/ safe, Commassie, Photography of DNA, RNA and protein Gels, Western blot membrane, Dot blot, Vis; UV (302, 365nm); Chemiluminescence AmershamTM Imager 600 Chemiluminescent Western blotting detection Cell counter Countess™ II Automated Cell Counter is a benchtop assay platform equipped with state-of-the-art optics, full autofocus, and image analysis software for rapid assessment of cells. ​ Accurate Fast Convenient Centrifuges MEGAFUGE 40R Capacity-500/250ml bottle, 50/15ml tube; Maximum speed: 15 200 rpm (depending on the rotor), 4 816xg; Temperature range: -10°C – 40°C FRESCO 17 Capacity-24 Eppendorf tube ; Maximum speed- 13 000 rpm depending on rotor, 17 000xg ; Temperature range- 5°C – 40°C MEGAFUGE 16R Capacity- 4x50ml/ 12x15ml ; Maximum speed Depending on Rotor – 15 200 rpm; 25 830xg ; Temperature range- -10°C – 40°C NUVE NF 400R Capacity: 4x50ml/ 8x15ml ; Maximum speed 4 100 rpm; Maximum RCF- 2 819xg ; Temperature range: -9°C – 40°C NUVE NF 800R Capacity: 4x50ml/ 12x15ml/ 24x1.5ml or 2ml/ 2 plates ; Maximum speed Swing-out Rotor: 4 100 rpm; Maximum RCF- 3 045xg ; Maximum speed Angle Rotor: 14 000 rpm; Maximum RCF: 18 405xg ; Temperature range: -9°C – 40°C DNA & Protein electrophoresis Transblot Detection & Analysis Protein or DNA electrophoresis Transblot SD semi dry Biorad- Transferring to a membrane by semi dry transfer system. Analysis by Commassie staining, immunoblotting: antibodies staining, and Imaging system. PCR PCR Thermocycler Blue-Ray biotech ​ Temperature range +4 °C-99 °C ; Fast heating ramp rate up to 5.5 °C/sec ; Excellent temperature accuracy and uniformity (+/- 0.3 °C) ; 12-section gradient temperature range from 1 to 24.9 °C for PCR optimization ; The quick boot-up takes only 45 seconds. Biometra Temperature range -3°C-99 °C temperature accuracy and uniformity (+/- 0.1 °C) Fusion FX 6 EDGE - Gel Imaging system Chemiluminescence Western, Northern or Southern blot Optional applications: DNA & RNA gels and fluorescence stain imaging with UV-Pad or Blue-Pad Colorimetric stained protein gels, X-Ray film, autorads, SSCP gels, colony dish and flask imaging with White- Light-Pad or UV-Pad + conversion screen Fluorescence Western blot with Spectra Capsules BioTek Synergy H1 Multimode Reader Synergy H1 offers continuously variable bandwidth monochromators for fluorescence excitation and em ission wavelength selection. Fluorescence bandwidth can be set between 9 and 50 nm, in 1 nm increments, allowing users to fully optimize reader settings to drive the best assay performance compared to fixed bandwidth systems. ​ UV-Vis Absorbance Fluorescence Intensity Luminescence Access to other instruments: ​ Ovens, Chemical & Biological Hoods, Shaker RT/37°C, Stirrer (Hot plate), dry bath 37°C, Heat Blocks, Vortex, Pipettes, Autoclave, Homogenizer, pH meter Liquid Nitrogen & -80°C storage. Contact us to learn more Current Companies | Start Up Here | Daren Labs START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact BIOTECH CANNABIS FOOD TECH AGRI TECH CLEAN TECH CHEMICAL Labs for Rent | Start Up Here | Daren Labs START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact Labs for Rent Start Up Here Innovation Center has been designed to meet the needs of those start-ups projects that need a laboratory or an office with various professional scientific services, allowing you to stay science focused. ​ You can start up quickly with a fully equipped lab or according to your budget. ​ The center support Biology, FoodTech, Chemistry, Materials, Agro-tech, Process, Medical Equipment and Life Science fields. Contact us to learn more The function of the center is to provide our clients with most of their operational ne eds This way, the innovator can remain devoted exclusively to his development work, without needing to invest time, money in infrastructure or take upon himself long term commitments, all aimed to increase the success rate for achieving milestones and grow . Labs Team | Start Up Here | Daren Labs START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact MEET THE TEAM M.Sc. Adi Zalik Sales Manager Ofer Daren Co-Founder & CEO Yuri Rusakovski Operations Manager Einav Ben David Administrative Manager Dr. Elena Shmerkin Lab operations & Safety Foodtech | Materials Experts | Daren Labs MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Food Tech Foods, whether natural or engineered, are complex chemical systems composed of various material families including fats, proteins, sugars, minerals and more. Moreover, foods undergo multiple physical and chemical processing before they are catered. Developing new food technologies is a huge challenge that required strong understanding of such materials and processes as well as relevant analytical skills and equipment. We can help you develop your new food products and provide you an objective, data-based outlook of your product, addressing topics such as: composition and water content, smell, texture, optimal storage and cooking conditions and much more. Serving some of the most prominent food tech companies in Israel today, we have gained significant experience and knowledge that can help you make you next leap forward. Contact us to learn more Testimonials | Start Up Here | Daren Labs START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact Testimonials “We had a lab ready within a day, which as a small start up, is the best imaginable thing. Daren Labs immediately understood our needs and developed a framework that facilitated every step of the company’s development. They even explained to us how the company can grow, develop and how they can support us with their services” Eshchar Ben-Shitrit, CEO, Redefine Meat “We received laboratories fitted with all the equipment we needed - biological & chemical systems, modern analytical equipment, which enabled quick and efficient analysis of our results. Due to this smooth start and achievements at Daren Labs during our first year, we were able to make a significant leap forward with our results” Dr. Neta Lavon, CTO, Aleph Farms “Daren unique labs are a significant ramp up for startups in the fields of life sciences, a place that provides a great value to the companies which are located there, and a one of it’s kind in Israel. With their help, we were able to establish the company's activities quickly, with maximum efficiency and a tremendous saving of resources and time - two things that are so important in the life of a start-up." Yuval Gilad, CEO & Co-Founder FreezeM "Their value model which enables small companies with limited budget to start laboratory activities immediately, without considerable initial investment and without the associated bureaucratic "headaches" . The model is very practical and allows companies to move forwards quickly. Above and beyond these technicalities, we appreciated the Daren Labs team that were helpful and professional (in consultations, safety, procurement, etc.) and no less important, their personal care. " Dr. Ori Cohavi, CTO & Co-Founder, Remilk I would like to warmly and with a heart full of appreciation recommend Daren Labs as a home for startups at the beginning.I will share here about the path Meat.The.End has taken with Daren and why I think it is the best place to start the activity of a new company. ​ Meat.The.End was founded during the Corona days, in 2020. After an initial period in which we worked from home and zoom, the time had come to move up a class and enter our own laboratories. I heard about Daren Laboratories from several foodtech and biotech companies who rented laboratories from them. Was recommended by everyone! I admit that there was some hesitation thinking that renting an independent place and doing everything ourselves would be cheaper. In the end, the decision was made to enter Daren, when the consideration was to save the necessary setup time and take advantage of the central location and proximity to other companies to "mingle" in an ecosystem that was new to us, when the plan was to stay for a period of one year. After signing a relatively short contract at first, we were given a laboratory and an office and started working immediately. Initially there were only three of us working in the company, but over time we realized that Daren also knew how to cater to our development needs, so we extended our stay there. When we left Daren, Meat.The.End already had a market-leading product, three major international customers and almost 20 employees. Now our new residence in Caesarea Industrial Park includes production line, laboratories, and offices with an area of ​​1000 square meters. When I look back at the consideration at the beginning about whether we should join Daren or become independent, I feel like it was not a discussion at all, for several reasons. ​ Cost. I learned that the rent was both effective and affordable. In addition to the investment required that must be carefully considered, the ongoing operation of a standalone company involves many expected and unexpected costs that can add up to a very significant budget burden. You will no longer have headaches. The long list of tasks for buildings maintenance and equipment takes time and becomes an administrative burden that, in my opinion, should be avoided at least during the first phase of the starup. Daren professionally handles the entire process, ensuring community residents have no worries, allowing us to focus on R&D and fundraising . Study . Our time in Daren was an opportunity to meet community partners. This is another critical point. At any given time, there are another 20 to 30 entrepreneurs and startups residing in Daren. This community helped us understand the issues and challenges faced by companies at similar or advanced stages to ours and we were surrounded with experienced, kind and pleasant people. Flexibility. Daren Labs ranks as a startup in everything, which may explain why Daren understands its tenants so well. For every request or question we had, there was always someone who understood our needs, knew how to deal with last-minute issues and took our difficulties into consideration. Daren's team is excellent, professional people and true friends – and will be at your side every day, always helping you in a good mood and a fun atmosphere. In addition to all the business advantages, I must personally mention the owner, Ofer Daren, who is one of the most conscientious, intelligent, fair and pleasant people I have ever met in the industry. The time at Nes Ziona was a formative time for Meat.The.End and thanks to Daren’s infrastructure and support we achieved a lot. It was a wonderful time for us to learn, develop and grow. Daren Lab’s contribution in promoting innovation inspires entrepreneurs and is worthy of praise." Dr. Ishai Mishor, Founder & CEO Meat.The.End Problem Solving | | Materials Experts | Daren Labs MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Problem Solving Production of physical products always involves materials processing. Whether in electronic circuits, fabrics, medical tubing or car tires, sometimes things go wrong. ​ In many cases, end-users and brand owners are not familiar with the various materials and processes involved in the making of their products and need our assistance. Identifying the root cause of a failed batch, loss of performance or change of color requires the application of multidisciplinary tools. Once identified, we recommend corrective actions and support our clients back to spec. ​ Some problems we helped solve: Plastic components showed poor bonding during production of medical device. Food package generating a strong smell after sealing process Unidentified “black spots” identified after production of a cosmetic lotion Degradation of the performance of a cooling fluid passing in new a multi materials system Variation of protection coating color used in electronics component manufacturing Contact us to learn more About Us | Daren Material Experts MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us About Us Daren Labs is an experienced problem-solver, offering special agility with interdisciplinary capabilities. We perform custom R&D and provide expert knowledge to commercial, government and private customers. We are also a serial SME participant in numerous European framework programs and maintain a full-time presence in the U.S. Recognizing the continuously growing needs of Israel’s entrepreneurial community, Daren Labs has leveraged its experience working alongside startup companies and investors to create the Daren Innovation Center, a technology-based accelerator. The Center provides an array of essential resources to early-stage projects, including dedicated laboratories, scientific guidance and professional consulting, all aimed at assisting startups to achieve their milestones with the highest rate of success. Daren Labs is a crossroad where industry, science, people and business opportunities meet Our Team Testimonials | Materials Experts | Daren Labs MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us " I would like to thank you and your team for doing an outstanding job in our engineered stenotic valve project. At the beginning of this project we did not know how much of what we aim for can be achieved, or even if it can be achieved at all. Still, not only did you achieve it, you also did it on a very short schedule. Specifically I would like to note Roni's professionalism and dedication; Roni had an invaluable contribution to the success of this project and was a pleasure to work with. Having a reliable bench model that can simulate the mechanical properties of a stenotic valve is very significant for our ability to evaluate our device. We appreciate your resilience and hard work and looking forward to our next collaboration." ​ Amir Revivo, R&D Pre Clinic Manager Daren General About Us | Daren Labs LAB RENTAL & SCIENTIFIC SERVICES FOR STARTUPS Daren Labs is a scientific consultancy with advanced R&D capabilities, connecting academy and industry in chemistry, polymers, materials and synthesis. Founded by Dr. Steve Daren in 1998, we today support a wide range of industries and academic institutes worldwide. Daren Labs is an experienced problem-solver, offering special agility with interdisciplinary capabilities. We perform custom R&D and provide expert knowledge to commercial, government and private customers. We are also a serial SME participant in numerous European framework programs and maintain a full-time presence in the U.S. FLEXIBILITY Being small and agile means we can find smarter, leaner and faster ways to change procedures, directions or methods to accommodate our client’s needs. EXTENSIVE KNOWLEDGE & EXPERIENCE For over 20 years of working across a wide range of industries, our team has gained unique knowledge and experience in advanced R&D projects. ABSOLUTE CONFIDENTIALITY All research and development projects performed for our clients are held in strict confidentiality. We make no IP claims for our research. Daren Labs is a crossroad where industry , science , people and business opportunities meet Get In Touch Previous 1 2 3 4 Next

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In-House Instruments PCR PCR Thermocycler Blue-Ray biotech Temperature range +4 °C-99 °C ; Fast heating ramp rate up to 5.5 °C/sec ; Excellent temperature accuracy and uniformity (+/- 0.3 °C) ; 12-section gradient temperature range from 1 to 24.9 °C for PCR optimization ; The quick boot-up takes only 45 seconds. Biometra Temperature range -3°C-99 °C temperature accuracy and uniformity (+/- 0.1 °C) RT-PCR Bio Rad CFX96TM - Analysis methods: PCR quantification, Gene expression, Melt curve analysis, Allelic discrimination, End point analysis ; Temperature range 0-100°C +/-0.2°C, Range of ext./em. 450-730nm ; 96 wells: from1μL-50 μL (recommended 10μL-25 μL). Mx3000p QPCR System Agilent - Mx3000p QPCR System Agilent - Analysis methods: Quantitative PCR, Comparative Quantitation, SYBR Green, Allele Discrimination, Melting curve. 4 dyes per well Microscope Olympus Fluorescence Microscope inverted CKX53 Olympus x4, x10, x20 + Fluorescence GFP, RFP, DAPI Brightfield, Phase Contrast, and DIC only Motic Optical Microscope x4, x10, x40, x100 + Camera 5M Olympus Binocular Microscope up to x90 + Camera 15M Plate reader Synergy HT Multi-Mode Microplate Reader - Capable of reading any plate format up to 384-well plates and provides temperature control up to 50° C and shaking as standard features. Typical applications include antibody-antigen binding, receptor-liquid binding, ELISA, nucleic acid quantitation Absorbance monochromator from 200 nm to 999 nm (UV -Vis). Fluorescence (ext./em. 485/530, 528/590, 485/590). Luminescence. Thermo scientific Multiskan FC - Plate types – 96 or 348 well plate ; Wavelength – 405nm, 450nm, 620nm ; Shaker – Slow (5 Hz, amplitude 15 mm), Medium (11 Hz, amplitude 3 mm), and Fast (20 Hz, amplitude 1 mm) ; Temperature range - +4°C to 50°C. PHOmo Microplate reader - Detection method: Absorbance ; Measurement modes: Endpoint & Kinetic ; Plate type: 96, 48 flat, U and V bottom ; Filters 405nm, 450nm, 492nm, 620nm. Flow cytometry CytoFLEX Beckman Coulter Life Science Flow cytometr - Laser specification- Violet (ex.405nm), Blue (ex.488), Red (ex.638). 30 000 events per second with all configured parameters. Nano Drop Micro-Spectrophotometer Fluorometer DeNovix DS-11 FX - Rapidly quantify seven orders of magnitude of nucleic acids and protein samples selecting your choice of UV-Vis or Fluorescent modes. Full spectrum UV-Vis analysis (190nm to 840 nm) Fluorescence capability: Green LED : 525 nm (Excitation), 565 to 650 nm (Emission) Red LED : 632 nm (Excitation), 665 to 740 nm (Emission) Blue LED : 470 nm (Excitation), 514 to 567 nm (Emission) UV : 375 nm (Excitation), 435 to 485 nm (Emission) NanoDrop 2000 Thermo Scientific - Applications: Nucleic acid, Protein, Fluorescent dye corporation, BCA Assays, Bradford, Kinetic methods, Custom methods ; Full spectral output (190 - 840 nm) ; Preconfigured methods for A260, A280, labeled DNA or Proteins, and much more. Imaging system Omega lum - Semi-Quantitative Assay EtBr, SYBR Green/ safe, Commassie, Photography of DNA, RNA and protein Gels, Western blot membrane, Dot blot, Vis; UV (302, 365nm); Chemiluminescence AmershamTM Imager 600 - Chemiluminescent Western blotting detection AKTA AKTA Avant 150 - Offers a complete solution for rapid, high-quality protein separations while maintaining flexibility and reliability. Analysis by spectrophotometry: wavelength 190-700nm & Conductimetry Cell counter Countess™ II Automated Cell Counter - is a benchtop assay platform equipped with state-of-the-art optics, full autofocus, and image analysis software for rapid assessment of cells. Accurate Fast Convenient Centrifuges MEGAFUGE 40R Capacity-500/250ml bottle, 50/15ml tube; Maximum speed: 15 200 rpm (depending on the rotor), 4 816xg; Temperature range: -10°C – 40°C FRESCO 17 Capacity-24 Eppendorf tube ; Maximum speed- 13 000 rpm depending on rotor, 17 000xg ; Temperature range- 5°C – 40°C MEGAFUGE 16R Capacity- 4x50ml/ 12x15ml ; Maximum speed Depending on Rotor – 15 200 rpm; 25 830xg ; Temperature range- -10°C – 40°C NUVE NF 400R Capacity: 4x50ml/ 8x15ml ; Maximum speed 4 100 rpm; Maximum RCF- 2 819xg ; Temperature range: -9°C – 40°C NUVE NF 800R Capacity: 4x50ml/ 12x15ml/ 24x1.5ml or 2ml/ 2 plates ; Maximum speed Swing-out Rotor: 4 100 rpm; Maximum RCF- 3 045xg ; Maximum speed Angle Rotor: 14 000 rpm; Maximum RCF: 18 405xg ; Temperature range: -9°C – 40°C DNA & Protein electrophoresis Transblot Detection & Analysis Protein or DNA electrophoresis Transblot SD semi dry – Biorad- Transferring to a membrane by semi dry transfer system. Analysis by Commassie staining, immunoblotting: antibodies staining, and Imaging system. Particle Size Analysis Particle size distribution & measurement HELOS/BR- Particle size analysis 0.1 µm - 875 µm, Dry or Wet dispersion ​​ Range R1, sub-micron module : 0.1 – 35 µm Range R3, Fourier lens module : 0.5 – 175 µm Range R5, top-micron module: 4.5 – 875 µm Access to other Instruments: Ovens, Chemical & Biological Hoods, Shaker RT/37°C, Stirrer (Hot plate), dry bath 37°C, Heat Blocks, Vortex, Pipettes, Autoclave, Homogenizer, pH meter Liquid Nitrogen & -80°C storage. Book a Space

DARREN INNOVATION CENTER About Us Labs for Rent Our Team Clients & Investors Book A Tour INTRODUCTION The Daren Innovation Center has been designed to meet the needs of those start-ups projects that need a laboratory and professional scientific support in such fields as Biology, Chemistry, Materials, Agro-tech, Process, Medical equipment and Life Science . ​ The function of the center is to provide our clients most of their logistic needs. This way, the innovator can remain devoted exclusively to his development work, without needing to invest time and money in infrastructure or take upon him self long term commitments, all aimed to to increase the success rate for achieving milestones and grow. The innovator can also receive technical and scientific support from experts in relevant fields who will assist in presenting the innovator to potential investors. We encourage entrepreneurs to contact us ; together we can hopefully find a way to start your new venture. A short and simple contract with no long term commitments Ideal for companies being funded by milestone Saving time and lawyers’ fees and avoiding bureaucracy and permits Instant start with administration by fellow scientists Full office facilities and maintainance Out of gallery Our center is a place where business opportunities can be found. For investors looking for "low profile", early-stage companies with a credible proven proof-of-concept our center is a good place to start. We often initiate and manage fund-matching operations for companies we recognize as promising. Join Our Offices Today

Investors seeking seed-stage business opportunities are welcome to contact us It is one of our goals, to help companies with good feasibility to find next-stage funding. ​ We invite investors to visit our center and meet potential start-ups before these companies are exposed to the general investor community. The companies we bring to the table all bear our stamp-of-validity technology-wise, as well as our personal acquaintance with the team behind the invention. Contact Us Start ups that grew with us: Harnessing cutting edge technologies to ensure food and environmental safety. ​ Learn More >> Presenting a unique technology in the field of extended storage and prolonged shelf life of cut flower. Learn More >> ​ ​ ITRODUCING

LABS FOR RENT The center is designed such that each innovator has his own work-place. The site includes an organic chemistry laboratory and nine other autonomous Biochemistry laboratories , each having its own basic equipment in. In addition there is an analytical room for general use. This includes Microscopes, FTIR, DSC, HPLC , TGA and more. Personal offices and storage facilities are also available. In additional to the infrastructure and equipment, an experienced staff of Chemists is available to support any project at short notice. Using this on-site manpower as needed, can save the heavy cost involved in employing permanent staff. Biology labs Chemistry labs Seminars Offices Electro chemistry lab Analytical equipment Out of gallery Our goal is to tailor for every innovator his own working place at minimum time and costs. To find out more about our lab rental services please contact us . ​ Contact Us