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Daren Labs is crossroads where industry, science , people and business opportunities meet DAREN STARTUP LABS Daren Startup Labs division is the leading co-working labs for startups with advanced workspaces. A place where you can test, develop and grow your ground-breaking ideas DAREN MATERIAL EXPERTS Daren Materials Experts division is a one-stop-shop for materials development and problem-solving, supporting the Israeli industry and startup eco-system providing results where chemistry and materials pose a significant challenge Daren Materials Experts division is a one-stop-shop for materials development and problem-solving, supporting the Israeli industry and startup eco-system providing results where chemistry and materials pose a significant challenge DAREN STARTUP LABS Daren Startup Labs division is the leading co-working labs for startups with advanced workspaces. A place where you can test, develop and grow your ground-breaking ideas More Info Daren Materials Experts division is a one-stop-shop for materials development and problem-solving, supporting the Israeli industry and startup eco-system providing results where chemistry and materials pose a significant challenge More Info

DAREN LABS IS ANSME WITH COMPREHENSIVE R&D CAPABILITIES Dr. Steve Daren has served on several occasions as an examiner for European Projects in the fifth and sixth frameworks. The experience gained has enabled him to introduce Daren Labs as a successful partner in a number of consortiums in the fifth, sixth and seventh frameworks. PROJECT ACRONYM Rapid Nanoprop Polymicro Brightlight Ephocell Inform TOPIC Reduction of agricultural and rural pollution by innovative additives Nanoclays in Flame-Retarded Polypropylene Polymer micro optics Laser Diode radiation Light Concentrator for photovoltaic Cells Nano formulations FRAMEWORK FP5 ​ ​ FP5 ​ Europractice ​ SME-1 cooperative research ​ FP7 ​ FP7 We welcome cooperation with companies and researchers who seek partnership in new projects Get In Touch

MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us About Us Daren Labs is an experienced problem-solver, offering special agility with interdisciplinary capabilities. We perform custom R&D and provide expert knowledge to commercial, government and private customers. We are also a serial SME participant in numerous European framework programs and maintain a full-time presence in the U.S. Recognizing the continuously growing needs of Israel’s entrepreneurial community, Daren Labs has leveraged its experience working alongside startup companies and investors to create the Daren Innovation Center, a technology-based accelerator. The Center provides an array of essential resources to early-stage projects, including dedicated laboratories, scientific guidance and professional consulting, all aimed at assisting startups to achieve their milestones with the highest rate of success. Daren Labs is a crossroad where industry, science, people and business opportunities meet Our Team

MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us MEET THE TEAM Dr. Steve Daren President & Founder ​ Dr. Elliot Silcoff VP R&D Dr. Anna Munder Chemistry Project Leader Sagi Daren Chief Business Officer ​ Vlada Nikolayevsky (MSc.) R&D Chemist & Lab Manager Pavel Basin (MSc.) R&D Chemist Dr. Nino Eliahu R&D Chemist & Operations Ofra Cohen Bookkeeper

MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us BIOTECH/PHARMA HI TECH MEDICAL TRADITIONAL INDUSTRY FIND OUT WHAT WHAT OUR CLIENTS SAY... Testimonials

START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact About Daren Startup Labs מרכז החדשנות Start Up Here הוקם כדי לענות על הצרכים של חברות הסטארט-אפ הזקוקות לתמיכה מדעית, מעבדתית ומקצועית כדי להמריץ את פיתוחן במינימום זמן ותקציב. ​ בדומה למודלים אחרים של חללי עבודה משותפים, אנו מציעים פתרונות Turn key להשכרת מעבדות ושירותים מדעיים. בדרך זו, סטארטאפים יכולים להמשיך להתמקד במו"פ שלהם ולהימנע מבזבוז מיותר של זמן וכסף, בהשקעה בתשתיות ולוגיסטיקה. Get In Touch You can start up quickly with a fully equipped lab or according to your budget Typical startups using our service module, include: Cleantech, Energy devices, Functional Materials, Biology, Food, Agrotech, water technology and more. Our Center is more than just a place to rent a lab space, it is a place where people meet, interact, share ideas and experience. Both our shared workspace labs sites are located in Ness Ziona, at the center of High-tech companies area. ​ The sites include private workspace, autonomous labs, offices, each having its own basic equipment. ​ A shared equipment room is available for general use, conference rooms and storage facilities. One is more focused on chemistry/materials and the other addressing biotechnology/pharma. ​ An experienced staff of Chemists and Biochemists are available to bring their extensive experience at short notice and reduced prices for the benefit of the resident companies. Contact us to learn more

MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Problem Solving Production of physical products always involves materials processing. Whether in electronic circuits, fabrics, medical tubing or car tires, sometimes things go wrong. ​ In many cases, end-users and brand owners are not familiar with the various materials and processes involved in the making of their products and need our assistance. Identifying the root cause of a failed batch, loss of performance or change of color requires the application of multidisciplinary tools. Once identified, we recommend corrective actions and support our clients back to spec. ​ Some problems we helped solve: Plastic components showed poor bonding during production of medical device. Food package generating a strong smell after sealing process Unidentified “black spots” identified after production of a cosmetic lotion Degradation of the performance of a cooling fluid passing in new a multi materials system Variation of protection coating color used in electronics component manufacturing Contact us to learn more

START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact Testimonials “We had a lab ready within a day, which as a small start up, is the best imaginable thing. Daren Labs immediately understood our needs and developed a framework that facilitated every step of the company’s development. They even explained to us how the company can grow, develop and how they can support us with their services” Eshchar Ben-Shitrit, CEO, Redefine Meat “We received laboratories fitted with all the equipment we needed - biological & chemical systems, modern analytical equipment, which enabled quick and efficient analysis of our results. Due to this smooth start and achievements at Daren Labs during our first year, we were able to make a significant leap forward with our results” Dr. Neta Lavon, CTO, Aleph Farms “Daren unique labs are a significant ramp up for startups in the fields of life sciences, a place that provides a great value to the companies which are located there, and a one of it’s kind in Israel. With their help, we were able to establish the company's activities quickly, with maximum efficiency and a tremendous saving of resources and time - two things that are so important in the life of a start-up." Yuval Gilad, CEO & Co-Founder FreezeM "Their value model which enables small companies with limited budget to start laboratory activities immediately, without considerable initial investment and without the associated bureaucratic "headaches" . The model is very practical and allows companies to move forwards quickly. Above and beyond these technicalities, we appreciated the Daren Labs team that were helpful and professional (in consultations, safety, procurement, etc.) and no less important, their personal care. " Dr. Ori Cohavi, CTO & Co-Founder, Remilk I would like to warmly and with a heart full of appreciation recommend Daren Labs as a home for startups at the beginning.I will share here about the path Meat.The.End has taken with Daren and why I think it is the best place to start the activity of a new company. ​ Meat.The.End was founded during the Corona days, in 2020. After an initial period in which we worked from home and zoom, the time had come to move up a class and enter our own laboratories. I heard about Daren Laboratories from several foodtech and biotech companies who rented laboratories from them. Was recommended by everyone! I admit that there was some hesitation thinking that renting an independent place and doing everything ourselves would be cheaper. In the end, the decision was made to enter Daren, when the consideration was to save the necessary setup time and take advantage of the central location and proximity to other companies to "mingle" in an ecosystem that was new to us, when the plan was to stay for a period of one year. After signing a relatively short contract at first, we were given a laboratory and an office and started working immediately. Initially there were only three of us working in the company, but over time we realized that Daren also knew how to cater to our development needs, so we extended our stay there. When we left Daren, Meat.The.End already had a market-leading product, three major international customers and almost 20 employees. Now our new residence in Caesarea Industrial Park includes production line, laboratories, and offices with an area of ​​1000 square meters. When I look back at the consideration at the beginning about whether we should join Daren or become independent, I feel like it was not a discussion at all, for several reasons. ​ Cost. I learned that the rent was both effective and affordable. In addition to the investment required that must be carefully considered, the ongoing operation of a standalone company involves many expected and unexpected costs that can add up to a very significant budget burden. You will no longer have headaches. The long list of tasks for buildings maintenance and equipment takes time and becomes an administrative burden that, in my opinion, should be avoided at least during the first phase of the starup. Daren professionally handles the entire process, ensuring community residents have no worries, allowing us to focus on R&D and fundraising . Study . Our time in Daren was an opportunity to meet community partners. This is another critical point. At any given time, there are another 20 to 30 entrepreneurs and startups residing in Daren. This community helped us understand the issues and challenges faced by companies at similar or advanced stages to ours and we were surrounded with experienced, kind and pleasant people. Flexibility. Daren Labs ranks as a startup in everything, which may explain why Daren understands its tenants so well. For every request or question we had, there was always someone who understood our needs, knew how to deal with last-minute issues and took our difficulties into consideration. Daren's team is excellent, professional people and true friends – and will be at your side every day, always helping you in a good mood and a fun atmosphere. In addition to all the business advantages, I must personally mention the owner, Ofer Daren, who is one of the most conscientious, intelligent, fair and pleasant people I have ever met in the industry. The time at Nes Ziona was a formative time for Meat.The.End and thanks to Daren’s infrastructure and support we achieved a lot. It was a wonderful time for us to learn, develop and grow. Daren Lab’s contribution in promoting innovation inspires entrepreneurs and is worthy of praise." Dr. Ishai Mishor, Founder & CEO Meat.The.End

LAB RENTAL & SCIENTIFIC SERVICES FOR STARTUPS Daren Labs is a scientific consultancy with advanced R&D capabilities, connecting academy and industry in chemistry, polymers, materials and synthesis. Founded by Dr. Steve Daren in 1998, we today support a wide range of industries and academic institutes worldwide. Daren Labs is an experienced problem-solver, offering special agility with interdisciplinary capabilities. We perform custom R&D and provide expert knowledge to commercial, government and private customers. We are also a serial SME participant in numerous European framework programs and maintain a full-time presence in the U.S. FLEXIBILITY Being small and agile means we can find smarter, leaner and faster ways to change procedures, directions or methods to accommodate our client’s needs. EXTENSIVE KNOWLEDGE & EXPERIENCE For over 20 years of working across a wide range of industries, our team has gained unique knowledge and experience in advanced R&D projects. ABSOLUTE CONFIDENTIALITY All research and development projects performed for our clients are held in strict confidentiality. We make no IP claims for our research. Daren Labs is a crossroad where industry , science , people and business opportunities meet Get In Touch

Materials Experts Materials Experts Home Services The Team Verticals Testimonials Contact Us More Download PDF Differential Scanning Calorimetry (DSC 6000 – Perkin Elmer) The differential scanning calorimeter (DSC) is a fundamental tool in thermal analysis. The information these instruments generate is used to understand amorphous and crystalline behavior, polymorph and eutectic transitions, curing and degree of cure, and many other material properties used to design, manufacture, and test products. It can be used in many industries – from pharmaceuticals and polymers, to nanomaterials and agrifood products. DSC analysis is used to measure melting temperature, heat of fusion, latent heat of melting, reaction energy and temperature, glass transition temperature, crystalline phase transition temperature and energy, precipitation energy and temperature, denaturation temperatures, oxidation induction times, and specific heat or heat capacity. By measuring the amount of energy absorbed or released by non-corrosive sample when it is heated or cooled, DSC analysis provide quantitative and qualitative data on endothermic (heat absorption) and exothermic (heat evolution) processes. Thermogravimetric analysis or thermal gravimetric analysis (TGA 8000– Perkin Elmer) Thermogravimetry Analysis (TGA) is the technology for measuring the relationship between mass and temperature (or time), under heating or cooling process, or under constant temperature, while the temperature is under control. TGA measures weight/mass change (loss or gain) and the rate of weight change as a function of temperature, time and atmosphere. Measurements are used primarily to determine the composition of materials and to predict their thermal stability. The technique can characterize materials that exhibit weight loss or gain due to sorption/desorption of volatiles, decomposition, oxidation and reduction. Mechanisms of Weight Change in TGA 1 Weight Loss: Decomposition: The breaking apart of chemical bonds. Evaporation: The loss of volatiles with elevated temperature. Reduction: Interaction of sample to a reducing atmosphere (hydrogen, ammonia, etc.). Desorption. 2 Weight Gain: Oxidation: Interaction of the sample with an oxidizing atmosphere. Absorption. All of these are kinetic processes (i.e. there is a rate at which they occur). Example: Characterization of Polymers Using TGA W.J. Sichina, Marketing Manager – Washinton dep.edu • Compositional analysis of multi-component materials or blends • Thermal stabilities • Oxidative stabilities • Estimation of product lifetimes • Decomposition kinetics • Effects of reactive atmospheres on materials • Filler content of materials • Moisture and volatiles content Other currents applications: Ceramics, Metal Materials, Flame Retardant, Carbon capture, Chemical loop, Vegetable Oil Oxidative Stability, Polymer Applications, and others Download PDF Spectrum obtained can be analysis compare We can analyze following type of samples Soft polymers, Rubbers, thin film* Soft powders, Pastes, Gels, Aqueous solutions Surface coatings Organic products Proteins and other biochemical Comparison of plant extract. Impurity included a pure reference sample. ​ Fourier transform infrared spectroscopy (FTIR ) FTIR is characterization technique used in qualitative material analysis within the biological, biomedical and chemical industry; this technique takes advantage of the vibrational transitions of a molecule and is widely used in organic synthesis, polymer science, petrochemical engineering, pharmaceutical industry and food analysis. FTIR is a method of measuring infrared absorption and emission spectra. In organic or inorganic compounds, IR Spectroscopy is used for checking presence of functional groups. The fundamental measurement obtained in infrared spectroscopy is an infrared spectrum, which is a plot of measured infrared intensity versus wavelength (or frequency) of light. Units of cm-1 is commonly used for wavenumber. *By transmission, analyzing of Thin Films* should be in the freestanding condition and thickness should be ≤ 50μm. Thicker film can be analyzed By ATR Attenuated total reflection (ATR) spectroscopy ATR is one accessory of FTIR spectrophotometer to measure surface properties of solid or thin film samples rather than their bulk properties. Generally, ATR has a penetration depth of around 1 or 2 micrometers depending on your sample conditions. The infrared radiation interacts with the sample through series of standing waves called evanescent waves, which penetrate the sample at each reflection point. An evanescent wave is produced each time the infrared beam is reflected from the inside surface of the crystal. Some of the energy of evanescent wave is absorbed by the sample and reflected radiation is returned to the detector. Link to website Download PDF Fourier transform infrared spectroscopy (FTIR ) ​ The technique is based on absorption of light. In molecular absorbance spectroscopy, a beam of ultraviolet or visible light is directed through a sample. Some of the light may be transmitted through the sample. Instrument measures transmitted light. Light that was not transmitted through the sample was absorbed. Absorbance (A) is defined as -log(P/Po). Beer Lambert Law States that absorbance of electromagnetic radiation by a given species is directly proportional to the concentration of the analyte. It is expressed as: A= εbC • where A is the absorbance, ε is the molar absorptivity, b is the path length and C is the concentration of analyte. Because ε and b are fixed under experimental conditions, the result is a linear relationship between absorbance and concentration. Download PDF Viscometer DV-II Brookfield The Brookfield DV-II+Pro Viscometer measures fluid viscosity at given shear rates. Viscosity is a measure of a fluid’s resistance to flow. The Viscometer rotates a sensing element in a fluid and measures the torque necessary to overcome the viscous resistance to the induced movement. This is accomplished by driving the immersed element, which is called a spindle, through a beryllium copper spring. The degree to which the spring is wound, indicated by the red pointer, is proportional to the viscosity of the fluid. All units of measurement are calculated in units of centipoise (cP); SI: 1 cP = 1 mPa•s Loss on Drying (LOD) ​ A method commonly used for moisture content determination is the loss-on-drying method. Occasionally it may refer to the loss of any volatile matter from the sample. Download PDF Freeze dryer or Lyophilizer ​ Lyophilizer and freeze dryer are synonymous names for the same equipment. A lyophilizer executes a water removal process typically used to preserve perishable materials, to extend shelf life or make the material more convenient for transport. Lyophilizers work by freezing the material, then reducing the pressure and adding heat to allow the frozen water in the material to sublimate. Controlled freeze-drying keeps the product temperature low enough during the process to avoid changes in the dried product appearance and characteristics. It is an excellent method for preserving a wide variety of heat-sensitive materials such as proteins, microbes, pharmaceuticals, tissues & plasma. High-performance liquid chromatography (HPLC) High performance liquid chromatography or commonly known as HPLC is an analytical technique used to separate, identify or quantify each component in a mixture. HPLC works following the basic principle of thin layer chromatography or column chromatography, where it has a stationary phase and a mobile phase. The mobile phase flows through the stationary phase and carries the components of the mixture with it. The mixture is separated and then identified and quantified by spectroscopy. A computer analyzes the data show the output in display.

START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact MEET THE TEAM Ofer Daren Co-Founder & CEO Yuri Rusakovski Chief Operating Officer M.Sc. Adi Zalik Sales Manager Einav Ben David Office Manager Dr. Elena Shmerkin Lab operations & Safety Lior Kadoshi Operations Assistant

MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS The Team Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Medical Devices Materials play a critical role in many medical devices and medical equipment. High performance polymers, adhesives and coatings are often used in piping, tubing and optical components. Dental applications require pH resistance, anti-bacterial properties alongside many other physical constrains such as hardness, formability, transparency and more. ​ During the years, Daren Labs has helped doctors, surgeons, innovators and engineers develop and improve new medical devices, from design-stage to development and manufacturing. Contact us to learn more