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השכרת מעבדות START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact DAREN GET IN TOUCH We will be happy to provide any additional information. Just leave your details below, and we will contact you. Full Name Email Company Phone Details Send Thanks for submitting! DAREN START UP HERE Tel. :08-9402942 Mail: info@darenlabs.com Fax :08-9409925 Address : 3 Pinhas Sapir St, Ness Ziona, 7403626 Israel

Our team helps companies and early-stage entrepreneurs to survey, separate, purify and analyze new alternative proteins and functional materials at milligram scale all the way to scale up and optimization. MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Alternative Proteins Rising demand for vegan and plant-based products is driving massive growth in alternative protein research and development. Innovation in this field involves the ability to identify and separate specific chemical groups extracted from various plants, vegetables and insects. After such functional groups isolated, various analytical methods can be applied including HPLC, LCMS and other to provide full chemical identification. Our team helps companies and early-stage entrepreneurs to survey, separate, purify and analyze new alternative proteins and functional materials at milligram scale all the way to scale up and optimization. Contact us to learn more

השכרת מעבדות START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact Labs for Rent Start Up Here Innovation Center has been designed to meet the needs of those start-ups projects that need a laboratory or an office with various professional scientific services, allowing you to stay science focused. You can start up quickly with a fully equipped lab or according to your budget. The center support Biology, FoodTech, Chemistry, Materials, Agro-tech, Process, Medical Equipment and Life Science fields. Contact us to learn more The function of the center is to provide our clients with most of their operational ne eds This way, the innovator can remain devoted exclusively to his development work, without needing to invest time, money in infrastructure or take upon himself long term commitments, all aimed to increase the success rate for achieving milestones and grow .

START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact Testimonials “We had a lab ready within a day, which as a small start up, is the best imaginable thing. Daren Labs immediately understood our needs and developed a framework that facilitated every step of the company’s development. They even explained to us how the company can grow, develop and how they can support us with their services” Eshchar Ben-Shitrit, CEO, Redefine Meat “We received laboratories fitted with all the equipment we needed - biological & chemical systems, modern analytical equipment, which enabled quick and efficient analysis of our results. Due to this smooth start and achievements at Daren Labs during our first year, we were able to make a significant leap forward with our results” Dr. Neta Lavon, CTO, Aleph Farms “Daren unique labs are a significant ramp up for startups in the fields of life sciences, a place that provides a great value to the companies which are located there, and a one of it’s kind in Israel. With their help, we were able to establish the company's activities quickly, with maximum efficiency and a tremendous saving of resources and time - two things that are so important in the life of a start-up." Yuval Gilad, CEO & Co-Founder FreezeM "Their value model which enables small companies with limited budget to start laboratory activities immediately, without considerable initial investment and without the associated bureaucratic "headaches" . The model is very practical and allows companies to move forwards quickly. Above and beyond these technicalities, we appreciated the Daren Labs team that were helpful and professional (in consultations, safety, procurement, etc.) and no less important, their personal care. " Dr. Ori Cohavi, CTO & Co-Founder, Remilk I would like to warmly and with a heart full of appreciation recommend Daren Labs as a home for startups at the beginning.I will share here about the path Meat.The.End has taken with Daren and why I think it is the best place to start the activity of a new company. Meat.The.End was founded during the Corona days, in 2020. After an initial period in which we worked from home and zoom, the time had come to move up a class and enter our own laboratories. I heard about Daren Laboratories from several foodtech and biotech companies who rented laboratories from them. Was recommended by everyone! I admit that there was some hesitation thinking that renting an independent place and doing everything ourselves would be cheaper. In the end, the decision was made to enter Daren, when the consideration was to save the necessary setup time and take advantage of the central location and proximity to other companies to "mingle" in an ecosystem that was new to us, when the plan was to stay for a period of one year. After signing a relatively short contract at first, we were given a laboratory and an office and started working immediately. Initially there were only three of us working in the company, but over time we realized that Daren also knew how to cater to our development needs, so we extended our stay there. When we left Daren, Meat.The.End already had a market-leading product, three major international customers and almost 20 employees. Now our new residence in Caesarea Industrial Park includes production line, laboratories, and offices with an area of 1000 square meters. When I look back at the consideration at the beginning about whether we should join Daren or become independent, I feel like it was not a discussion at all, for several reasons. Cost. I learned that the rent was both effective and affordable. In addition to the investment required that must be carefully considered, the ongoing operation of a standalone company involves many expected and unexpected costs that can add up to a very significant budget burden. You will no longer have headaches. The long list of tasks for buildings maintenance and equipment takes time and becomes an administrative burden that, in my opinion, should be avoided at least during the first phase of the starup. Daren professionally handles the entire process, ensuring community residents have no worries, allowing us to focus on R&D and fundraising . Study . Our time in Daren was an opportunity to meet community partners. This is another critical point. At any given time, there are another 20 to 30 entrepreneurs and startups residing in Daren. This community helped us understand the issues and challenges faced by companies at similar or advanced stages to ours and we were surrounded with experienced, kind and pleasant people. Flexibility. Daren Labs ranks as a startup in everything, which may explain why Daren understands its tenants so well. For every request or question we had, there was always someone who understood our needs, knew how to deal with last-minute issues and took our difficulties into consideration. Daren's team is excellent, professional people and true friends – and will be at your side every day, always helping you in a good mood and a fun atmosphere. In addition to all the business advantages, I must personally mention the owner, Ofer Daren, who is one of the most conscientious, intelligent, fair and pleasant people I have ever met in the industry. The time at Nes Ziona was a formative time for Meat.The.End and thanks to Daren’s infrastructure and support we achieved a lot. It was a wonderful time for us to learn, develop and grow. Daren Lab’s contribution in promoting innovation inspires entrepreneurs and is worthy of praise." Dr. Ishai Mishor, Founder & CEO Meat.The.End

Subcontracting your R&D projects isn’t an easy decision to make. However, with the right partner contract R&D can be a cost-effective way to get results, faster. MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Contract R&D Subcontracting your R&D projects isn’t an easy decision to make. However, with the right partner contract R&D can be a cost-effective way to get results, faster. Our team of experts leads dozens of materials-development project annually, working closely with our clients, making sure results meet the goal. Our long-year diverse experience, in-house lab infrastructure and analytics, allow us to develop custom solutions efficiently. In cases of specialty materials development, we are also able to manufacturer the developed product (kilo scale batches). Some contract R&D projects we can mention: Development of polymeric membrane for flexible batteries (technology commercialized). Developed cross-linking procedures for hyaluronic acid hydrogels Developed and scaled up a five-stage synthesis of a new steroid drug for Fatty Liver Disease (now in phase III trials) Reverse engineering and pilot production of a bio-degradable polymer for orthopedic implants. Development of UV sensitive photochromic coating for optical equipment. Daren labs produces this material for the OEM. Developed an acrylic surface coating that enhances the shelf-life of cut flowers (technology commercialized). Contact us to learn more

Production of physical products always involves materials processing. MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Problem Solving Production of physical products always involves materials processing. Whether in electronic circuits, fabrics, medical tubing or car tires, sometimes things go wrong. In many cases, end-users and brand owners are not familiar with the various materials and processes involved in the making of their products and need our assistance. Identifying the root cause of a failed batch, loss of performance or change of color requires the application of multidisciplinary tools. Once identified, we recommend corrective actions and support our clients back to spec. Some problems we helped solve: Plastic components showed poor bonding during production of medical device. Food package generating a strong smell after sealing process Unidentified “black spots” identified after production of a cosmetic lotion Degradation of the performance of a cooling fluid passing in new a multi materials system Variation of protection coating color used in electronics component manufacturing Contact us to learn more

START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact About Daren Startup Labs Ignite Your Innovation at Start Up Here Start Up Here Innovation Center was founded with one mission: to empower start-ups with the scientific, laboratory, and professional support they need to bring ideas to life faster and smarter, with minimal resources. Unlike traditional setups, we provide ready-to-go, turnkey lab spaces and scientific services designed to remove barriers and keep your team focused on what matters most innovation. By taking infrastructure and logistics off your plate, we save you time, money, and headache, so you can accelerate your R&D and scale your vision without compromise . Get In Touch You can start up quickly with a fully equipped lab or according to your budget Typical startups using our service module, include: Cleantech, Energy devices, Functional Materials, Biology, Food, Agrotech, water technology and more. Our Center is more than just a place to rent a lab space, it is a place where people meet, interact, share ideas and experience. Both our shared workspace labs sites are located in Ness Ziona, at the center of High-tech companies area. The sites include private workspace, autonomous labs, offices, each having its own basic equipment. A shared equipment room is available for general use, conference rooms and storage facilities. One is more focused on chemistry/materials and the other addressing biotechnology/pharma. An experienced staff of Chemists and Biochemists are available to bring their extensive experience at short notice and reduced prices for the benefit of the resident companies. Contact us to learn more

MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us " I would like to thank you and your team for doing an outstanding job in our engineered stenotic valve project. At the beginning of this project we did not know how much of what we aim for can be achieved, or even if it can be achieved at all. Still, not only did you achieve it, you also did it on a very short schedule. Specifically I would like to note Roni's professionalism and dedication; Roni had an invaluable contribution to the success of this project and was a pleasure to work with. Having a reliable bench model that can simulate the mechanical properties of a stenotic valve is very significant for our ability to evaluate our device. We appreciate your resilience and hard work and looking forward to our next collaboration." Amir Revivo, R&D Pre Clinic Manager

We help you develop your new food products and provide you an objective, data-based outlook addressing topics such as composition and water content, smell, texture, optimal storage and cooking conditions and more. MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us Food Tech Foods, whether natural or engineered, are complex chemical systems composed of various material families including fats, proteins, sugars, minerals and more. Moreover, foods undergo multiple physical and chemical processing before they are catered. Developing new food technologies is a huge challenge that required strong understanding of such materials and processes as well as relevant analytical skills and equipment. We can help you develop your new food products and provide you an objective, data-based outlook of your product, addressing topics such as: composition and water content, smell, texture, optimal storage and cooking conditions and much more. Serving some of the most prominent food tech companies in Israel today, we have gained significant experience and knowledge that can help you make you next leap forward. Contact us to learn more

START UP HERE About Us Labs for Rent Equipment Team Our Graduates Testimonials Contact Lab Design And Construction Over the years we have gained a unique capability – designing and building of labs. Building a lab, on time and budget, taking into consideration the needs of the R&D team while complying with the rigorous (and sometimes cumbersome) requirements of the fire department, health & environment office, municipalities and more is not an easy task. Mistakes can be painful and cost time and money. Still, with more than 3 large lab facilities successfully built and more than 20 years of lab operation and maintenance – we offer our experience to others seeking to build a lab of their own. We can consult during the design process and help you through execution making sure you avoid critical mistakes, from the selection of the right floor material through to the purchasing of chemical hoods – we will be there for you. If you are thinking of building you own lab, let us know, we can help you do it right the first time! Get In Touch

Materials Experts Materials Experts Home Services The Team Accessibility Statement Verticals Testimonials Contact Us More Download PDF Differential Scanning Calorimetry (DSC 6000 – Perkin Elmer) The differential scanning calorimeter (DSC) is a fundamental tool in thermal analysis. The information these instruments generate is used to understand amorphous and crystalline behavior, polymorph and eutectic transitions, curing and degree of cure, and many other material properties used to design, manufacture, and test products. It can be used in many industries – from pharmaceuticals and polymers, to nanomaterials and agrifood products. DSC analysis is used to measure melting temperature, heat of fusion, latent heat of melting, reaction energy and temperature, glass transition temperature, crystalline phase transition temperature and energy, precipitation energy and temperature, denaturation temperatures, oxidation induction times, and specific heat or heat capacity. By measuring the amount of energy absorbed or released by non-corrosive sample when it is heated or cooled, DSC analysis provide quantitative and qualitative data on endothermic (heat absorption) and exothermic (heat evolution) processes. Thermogravimetric analysis or thermal gravimetric analysis (TGA 8000– Perkin Elmer) Thermogravimetry Analysis (TGA) is the technology for measuring the relationship between mass and temperature (or time), under heating or cooling process, or under constant temperature, while the temperature is under control. TGA measures weight/mass change (loss or gain) and the rate of weight change as a function of temperature, time and atmosphere. Measurements are used primarily to determine the composition of materials and to predict their thermal stability. The technique can characterize materials that exhibit weight loss or gain due to sorption/desorption of volatiles, decomposition, oxidation and reduction. Mechanisms of Weight Change in TGA 1 Weight Loss: Decomposition: The breaking apart of chemical bonds. Evaporation: The loss of volatiles with elevated temperature. Reduction: Interaction of sample to a reducing atmosphere (hydrogen, ammonia, etc.). Desorption. 2 Weight Gain: Oxidation: Interaction of the sample with an oxidizing atmosphere. Absorption. All of these are kinetic processes (i.e. there is a rate at which they occur). Example: Characterization of Polymers Using TGA W.J. Sichina, Marketing Manager – Washinton dep.edu • Compositional analysis of multi-component materials or blends • Thermal stabilities • Oxidative stabilities • Estimation of product lifetimes • Decomposition kinetics • Effects of reactive atmospheres on materials • Filler content of materials • Moisture and volatiles content Other currents applications: Ceramics, Metal Materials, Flame Retardant, Carbon capture, Chemical loop, Vegetable Oil Oxidative Stability, Polymer Applications, and others Download PDF Spectrum obtained can be analysis compare We can analyze following type of samples Soft polymers, Rubbers, thin film* Soft powders, Pastes, Gels, Aqueous solutions Surface coatings Organic products Proteins and other biochemical Comparison of plant extract. Impurity included a pure reference sample. Fourier transform infrared spectroscopy (FTIR ) FTIR is characterization technique used in qualitative material analysis within the biological, biomedical and chemical industry; this technique takes advantage of the vibrational transitions of a molecule and is widely used in organic synthesis, polymer science, petrochemical engineering, pharmaceutical industry and food analysis. FTIR is a method of measuring infrared absorption and emission spectra. In organic or inorganic compounds, IR Spectroscopy is used for checking presence of functional groups. The fundamental measurement obtained in infrared spectroscopy is an infrared spectrum, which is a plot of measured infrared intensity versus wavelength (or frequency) of light. Units of cm-1 is commonly used for wavenumber. *By transmission, analyzing of Thin Films* should be in the freestanding condition and thickness should be ≤ 50μm. Thicker film can be analyzed By ATR Attenuated total reflection (ATR) spectroscopy ATR is one accessory of FTIR spectrophotometer to measure surface properties of solid or thin film samples rather than their bulk properties. Generally, ATR has a penetration depth of around 1 or 2 micrometers depending on your sample conditions. The infrared radiation interacts with the sample through series of standing waves called evanescent waves, which penetrate the sample at each reflection point. An evanescent wave is produced each time the infrared beam is reflected from the inside surface of the crystal. Some of the energy of evanescent wave is absorbed by the sample and reflected radiation is returned to the detector. Link to website Download PDF Fourier transform infrared spectroscopy (FTIR ) The technique is based on absorption of light. In molecular absorbance spectroscopy, a beam of ultraviolet or visible light is directed through a sample. Some of the light may be transmitted through the sample. Instrument measures transmitted light. Light that was not transmitted through the sample was absorbed. Absorbance (A) is defined as -log(P/Po). Beer Lambert Law States that absorbance of electromagnetic radiation by a given species is directly proportional to the concentration of the analyte. It is expressed as: A= εbC • where A is the absorbance, ε is the molar absorptivity, b is the path length and C is the concentration of analyte. Because ε and b are fixed under experimental conditions, the result is a linear relationship between absorbance and concentration. Download PDF Viscometer DV-II Brookfield The Brookfield DV-II+Pro Viscometer measures fluid viscosity at given shear rates. Viscosity is a measure of a fluid’s resistance to flow. The Viscometer rotates a sensing element in a fluid and measures the torque necessary to overcome the viscous resistance to the induced movement. This is accomplished by driving the immersed element, which is called a spindle, through a beryllium copper spring. The degree to which the spring is wound, indicated by the red pointer, is proportional to the viscosity of the fluid. All units of measurement are calculated in units of centipoise (cP); SI: 1 cP = 1 mPa•s Loss on Drying (LOD) A method commonly used for moisture content determination is the loss-on-drying method. Occasionally it may refer to the loss of any volatile matter from the sample. Download PDF Freeze dryer or Lyophilizer Lyophilizer and freeze dryer are synonymous names for the same equipment. A lyophilizer executes a water removal process typically used to preserve perishable materials, to extend shelf life or make the material more convenient for transport. Lyophilizers work by freezing the material, then reducing the pressure and adding heat to allow the frozen water in the material to sublimate. Controlled freeze-drying keeps the product temperature low enough during the process to avoid changes in the dried product appearance and characteristics. It is an excellent method for preserving a wide variety of heat-sensitive materials such as proteins, microbes, pharmaceuticals, tissues & plasma. High-performance liquid chromatography (HPLC) High performance liquid chromatography or commonly known as HPLC is an analytical technique used to separate, identify or quantify each component in a mixture. HPLC works following the basic principle of thin layer chromatography or column chromatography, where it has a stationary phase and a mobile phase. The mobile phase flows through the stationary phase and carries the components of the mixture with it. The mixture is separated and then identified and quantified by spectroscopy. A computer analyzes the data show the output in display.

For any question or for scheduling an appointment with our experts contact MATERIALS EXPERTS Materials Experts Home Services Contract R&D Scale up & Production Problem Solving Expert Opinion Analytical Capabilities DaaS Tech Scouting The Team Accessibility Statement Verticals Food Tech Energy and Cleantech Pharma Alternative Proteins Medical Devices Traditional Industries Testimonials Client Portfolio Contact Us MEET THE TEAM Dr. Steve Daren President & Founder Dr. Shai Garty R&D Project Leader Dr. Anna Munder R&D Project Leader Sagi Daren Chief Business Officer Pavel Basin (MSc.) R&D Chemist Ofra Cohen Bookkeeper ... ...